Science issues correction on a paper after repeat experiments and misconduct finding

Two months after publishing the article "Structural basis for strychnine activation of human bitter taste receptor TAS2R46" in September 2022, Science issued an editorial expression of concern, stating a post-publication analysis had found one figure with "potential discrepancies".
The authors worked with "outside experts" to repeat aspects of the experiment, told Meagan Phelan, communications director for Science. They "repeated bioluminescence energy transfer experiments" that were the basis for two of the article’s figures, one of which was the focus of the 2022 expression of concern, the new 2025 notice states. Both figures were removed from the corrected study.
The erratum also says Xiaoling Cao was removed as an author. The authors discovered Cao had "committed misconduct" during the original study and was responsible for the removed aspects of the paper, so "no longer qualified for authorship".
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